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Why 2 Doses?

In a study of 105 patients, 35% of people with severe allergic reactions required a second dose of epinephrine to reverse their symptoms. It is important that the symptoms subside significantly within the first ten minutes of the injection. If they don’t you have to be prepared with a back-up dose. That’s why Twinject comes with two doses.

World Health Organization (WHO) and Anaphylaxis Canada recommend that you always have a second dose available, or one dose for every 10 to 20 minutes of travel time to a medical emergency facility.

Biphasic Anaphylactic Reactions

Some people have what is called a biphasic reaction – that means that symptoms, once over, will actually return. This type of reaction occurs in 20% of cases. Unfortunately there are no markers or signs that allow your doctor to predict if you are susceptible to a biphasic reaction. That means carrying a back-up dose is vitally important. Usually the symptoms subside and then reoccur one to 8 hours following the initial reaction but can reoccur up to 38 hours later.


We’ve designed the Twinject auto-injector to be very convenient to carry and really easy to use.

As you will see in the training section, simple red/green, one-two colour coding will help you remember what to do when you have to respond to a real emergency. It really is as easy to use as 1-2-Inject.

But you do have to read the instructions carefully and we strongly recommend that you watch the video and follow the step-by-step instructions with pictures.

Fatalities occur because people forget to carry their epinephrine with them. Carry Twinject all the time and stay trained.